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Premier Biosoft International, Broad Institute

Premier Biosoft International last week launched TMA Foresight, a statistical tool for tissue microarray data analysis designed for pathologists, clinicians, and researchers.

According to Premier Biosoft, TMA Foresight can be used for applications such as simple descriptive statistics that include mean, sum, and variance, as well as more advanced data correlation such as hierarchical clustering and Kaplan Meier plots, which can be used for prognostic marker identification.


Scientists from the Broad Institute have released Gene Set Enrichment Analysis 2.0, an enhanced version of the Broad’s previously released gene expression-analysis tool that uses a multi-gene approach to extract information from microarray data.
According to the Broad, the GSEA software now includes more than 1,000 additional gene sets as well as a gene set browser, which can pinpoint specific gene sets based on a particular gene or other parameter of interest. GSEA 2.0 also enables users to graphically analyze leading-edge, high-scoring gene sets.
The updated software can be accessed here.

The Scan

Renewed Gain-of-Function Worries

The New York Times writes that the pandemic is renewing concerns about gain-of-function research.

Who's Getting the Patents?

A trio of researchers has analyzed gender trends in biomedical patents issued between 1976 and 2010 in the US, New Scientist reports.

Other Uses

CBS Sunday Morning looks at how mRNA vaccine technology could be applied beyond SARS-CoV-2.

PLOS Papers Present Analysis of Cervicovaginal Microbiome, Glycosylation in Model Archaea, More

In PLOS this week: functional potential of the cervicovaginal microbiome, glycosylation patterns in model archaea, and more.