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Patent Watch: Jan 6, 2009

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Ocimum Biosolutions of Indianapolis has received US Patent No. 7,469,185, “Primary rat hepatocyte toxicity modeling.” The patent claims a method for determining whether a test compound is a liver toxin by: a) exposing liver tissue or liver cells to the test compound; b) preparing a normalized gene expression profile of at least ten genes for the liver tissue or liver cells; c) comparing the gene expression profile to a hepatotoxicity model; and d) scoring the comparison to determine whether the test compound is a hepatotoxin.
 

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