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NimbleGen, Affymetrix, Nanogen, VizX


NimbleGen Systems has launched services using its new ENCODE microarray, based on content generated by the Encyclopedia of DNA Elements Project Consortium. The array contains more than 384,000 unique 50mer probes selected from 30 megabases of human sequence data specified by the consortium. NimbleGen is one of two micro-array firms to participate in the ENCODE project. The launch of NimbleGen’s array follows the launch of Affymetrix’s ENCODE01 array, based on the same project, last month (see BAN 10/27/2004).

Affymetrix has introduced 179 NimbleExpress prokaryotic array designs. The arrays are manufactured by NimbleGen for Affymetrix under a pact signed earlier this year. Affymetrix said the arrays will enable researchers to study the whole-genome expression of many pathogenic organisms such as Bacillus anthracis, Haemophilus influenzae, and Mycobacterium tuberculosis.

Nanogen has announced the development of analyte-specific reagents for detecting six common respiratory viruses in a single panel. The panel includes ASRs for influenza A, influenza B, human parainfluenza 1, human parainfluenza 2, human parainfluenza 3, and respiratory syncytial virus A/B. The ASRs will run on Nanogen’s NanoChip 400, the firm’s recently introduced second-generation microarray-based instrument, and will be available to clinical labs in early 2005 (see BAN 11/3/2004 for more information).

VizX has launched the GeneSifter Jumpstart microarray data analysis package for Affymetrix GeneChip users. The package provides written reports of statistical and biological analysis of data, WebEx presentations that demonstrate how the analysis was performed, and data prepared for further analysis by GeneSifter science support staff. It also provides an option for submission of microarray data to the GEO public data repository.


The Scan

Purnell Choppin Dies

Purnell Choppin, a virologist who led the Howard Hughes Medical Institute, has died at 91, according to the Washington Post.

Effectiveness May Decline, Data From Israel Suggests

The New York Times reports that new Israeli data suggests a decline in Pfizer-BioNTech SARS-CoV-2 vaccine effectiveness against Delta variant infection, though protection against severe disease remains high.

To See Future Risk

Slate looks into the use of polygenic risk scores in embryo screening.

PLOS Papers on Methicillin-Resistant Staphylococcus, Bone Marrow Smear Sequencing, More

In PLOS this week: genomic analysis of methicillin-resistant Staphylococcus pseudintermedius, archived bone marrow sequencing, and more.