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NIH Gives Fluidigm and Berkeley Lab $1M to Develop Microfluidic Chip

NEW YORK (GenomeWeb News) — Fluidigm and the Lawrence Berkeley National Laboratory have received $1 million from the National Institutes of Health to develop a microfluidic chip to collect in situ X-ray diffraction data.
 
The chip will enable researchers to screen protein crystals at a synchrotron without first having to remove them from the chip.
 
The grant is for two years. According to a statement, the chip would allow researchers to identify the best crystals for diffraction experiment using actual X-ray data rather than relying on quantitative measures.

This article originally appeared in ProteoMonitor, a GenomeWeb News sister publication.

The Scan

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Researchers report in Science Translational Medicine that the accumulation of LINE-1 RNA contributes to premature aging conditions and that symptoms can be improved by targeting them.

Team Presents Cattle Genotype-Tissue Expression Atlas

Using RNA sequences representing thousands of cattle samples, researchers looked at relationships between cattle genotype and tissue expression in Nature Genetics.

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With whole-genome sequences for dozens of individuals from the Nama population, researchers saw in Genome Biology fine-scale recombination patterns that clustered outside of other populations.

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While sequencing individuals from a multi-generation family, researchers identified a myotonic dystrophy type 2-related short tandem repeat in the European Journal of Human Genetics.