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NGK Insulators, Qiagen, Zyomyx

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NGK Insulators of Nagoya, Japan, has received US Patent Number 6,365,378, “Method for producing DNA chip.” The patent covers a method wherein a DNA fragment is amplified by PCR, then the product is dried into a DNA powder. This powder is then added to sample-pouring ports in micropipettes of a dispenser, and a buffer solution is poured from the port into a cavity to prepare a sample solution. This solution is then discharged by an actuator onto a base plate.

 

Qiagen of Venlo, the Netherlands, has just received US Patent Number 6,365,349, “Apparatus and methods for arraying solution onto a solid support.” The patent covers a method in which a planar tip of a spring probe is immersed into a solution of biomolecules — preferably oligonucleotides — with a thickening agent, then removed from the solution with sample adhering to the tip, and transferred to a solid support.

 

Zyomyx of Hayward, Calif., has been awarded US Patent Number 6,365,418, “Arrays of protein capture agents and methods of use thereof.” The patent covers Zyomyx’s arrays of protein-capture agents that are expressed in cells. It describes different antibody arrays and uses for patterns of cellular protein expression.

“The state-of-the-art protein chip technology covered in this patent is the second critical element of our emerging broad patent estate,” said Lawrence Cohen, Zyomyx chief executive officer, in a statement. “Together with the ‘Non-Specific Binding Resistant Border’ technology patent recently issued to Zyomyx, today’s patent issuance positions Zyomyx as a dominant player in the protein biochip market by giving broad exclusive rights to key surface chemistry configurations.”

The Scan

And Back

The New York Times reports that missing SARS-CoV-2 genome sequences are back in a different database.

Lacks Family Hires Attorney

A lawyer for the family of Henrietta Lacks plans to seek compensation from pharmaceutical companies that have used her cancer cells in product development, the Baltimore Sun reports.

For the Unknown

The Associated Press reports that family members are calling on the US military to use new DNA analysis techniques to identify unknown sailors and Marines who were on the USS Arizona.

PLOS Papers on Congenital Heart Disease, COVID-19 Infection Host MicroRNAs, Multiple Malformation Mutations

In PLOS this week: new genes linked to congenital heart disease, microRNAs with altered expression in COVID-19, and more.