Skip to main content
Premium Trial:

Request an Annual Quote

New Products: Plexpress and MediSapiens' OncoTRAC Gene Expression Service

Premium

Plexpress and MediSapiens this week launched their collaborative OncoTRAC Gene Expression Service.

Users of the service gain access to MediSapiens' IST Online gene expression database to identify relevant genes of interest. After this discovery phase, Plexpress' TRAC gene expression analysis platform is used to assay the expression of a selected 30-gene panel in a large number of samples.

The companies said the service supports customer projects from gene discovery through to validation and in-depth study, and across drug development, biomarker discovery, and life science research applications.

Plexpress' TRAC platform relies on a set of amplifiable detection probes and biotinylated oligo-capture probes that are hybridized in solution. The resulting sandwich hybrids are collected on magnetic streptavidin-coated microparticles and washed. The hybridized probes are then eluted and detected with laser-induced fluorescence and capillary electrophoresis. TRAC has been adapted to work in a 96-well format, allowing users to profile the expression of 30 genes in each well, according to the company.

The Scan

Mosquitos Genetically Modified to Prevent Malaria Spread

A gene drive approach could be used to render mosquitos unable to spread malaria, researchers report in Science Advances.

Gut Microbiomes Allow Bears to Grow to Similar Sizes Despite Differing Diets

Researchers in Scientific Reports find that the makeup of brown bears' gut microbiomes allows them to reach similar sizes even when feasting on different foods.

Finding Safe Harbor in the Human Genome

In Genome Biology, researchers present a new approach to identify genomic safe harbors where transgenes can be expressed without affecting host cell function.

New Data Point to Nuanced Relationship Between Major Depression, Bipolar Disorder

Lund University researchers in JAMA Psychiatry uncover overlapping genetic liabilities for major depression and bipolar disorder.