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New Product Watch: Aug 2, 2011

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BlueGnome this week launched two SNP microarrays to detect copy number imbalance at high resolution and loss of heterozygosity/uniparental isodysomy in the same assay.

The company has introduced the CytoChip SNP 4x180K array for the investigation of constitutional samples. The new chip is based on the International Standards for Cytogenomic Arrays consortium's consensus design, and includes SNP-specific probes that enable 10-megabase LOH detection.

The second new array, called CytoChip Cancer SNP 4x180K, includes a gene-enriched design for copy number imbalance, plus SNP probes that offer 5-megabase LOH detection. BlueGnome said that it intends to extend the range of SNP array designs available in the future.

A company spokesperson told BioArray News this week that the new chips are manufactured by Agilent Technologies. She said that one advantage of using a SNP array is that "you can detect conditions caused by UPD/LOH, which would be missed by array [comparative genomic hybridization] alone," as they are copy-number-neutral aberrations.


OriGene Technologies this month released the latest version of its TrueMAB monoclonal antibodies portfolio. The launch expands the company's offering to more than 7,500 antibodies in total. The antibodies can be used in various immunoassays, including those based on protein microarrays.

The Scan

Genetic Risk Factors for Hypertension Can Help Identify Those at Risk for Cardiovascular Disease

Genetically predicted high blood pressure risk is also associated with increased cardiovascular disease risk, a new JAMA Cardiology study says.

Circulating Tumor DNA Linked to Post-Treatment Relapse in Breast Cancer

Post-treatment detection of circulating tumor DNA may identify breast cancer patients who are more likely to relapse, a new JCO Precision Oncology study finds.

Genetics Influence Level of Depression Tied to Trauma Exposure, Study Finds

Researchers examine the interplay of trauma, genetics, and major depressive disorder in JAMA Psychiatry.

UCLA Team Reports Cost-Effective Liquid Biopsy Approach for Cancer Detection

The researchers report in Nature Communications that their liquid biopsy approach has high specificity in detecting all- and early-stage cancers.