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New Product Watch: Mar 10, 2009


Febit this week said that its microRNA Geniom biochips have been updated to reflect the updated content of miRBase version 13.0, which was released by the Wellcome Trust Sanger Institute this week.

MiRBase 13.0 contains 9,539 entries, compared to 8,619 in version 12.0, launched last September. It contains 937 new hairpin sequences, and 1,004 novel mature miR and miR* products have been added, Febit said.

Febit's biochips are available as catalog products for use on its RT Analyzer instrument, via its profiling service, and also can be synthesized by labs that own one of the firm's Geniom instruments.

DNAStar this week launched ArrayStar version 3.0, which includes new functionality in the areas of normalization, gene ontology, and data transformations, the firm said.

The software also has an optional module called QSeq that is designed to accept sequence data from second-generation sequencing platforms and use it in digital gene expression and RNA-Seq applications, DNAStar said.

Premier Biosoft has launched AlleleID version 7.01. The software analysis tool for qPCR and microarray oligonucleotide design now includes support for the latest design guidelines laid down by MRC-Holland, the Dutch provider of multiplex ligation-dependent probe amplification technology.

AlleleID now also supports the UCSC genome browser file format, developed and maintained by the Genome Bioinformatics Group at the University of California at Santa Cruz. Premier said that AlleleID 7.01 includes an enhanced automatic homology avoidance algorithm that enables users to design assays with greater specificity, avoiding unrelated SNPs at the same time.

The Scan

Suicidal Ideation-Linked Loci Identified Using Million Veteran Program Data

Researchers in PLOS Genetics identify risk variants within and across ancestry groups with a genome-wide association study involving veterans with or without a history of suicidal ideation.

Algorithm Teases Out Genetic Ancestry in Individuals at Biobank Scale

Researchers develop an algorithm known as Rye to tease apart ancestry fractions in admixed individuals at a biobank-scale, applying it to 488,221 UK Biobank participants in Nucleic Acids Research.

Multi-Ancestry Analysis Highlights Comparable Common Variants at Complex Trait-Linked Loci

Researchers in Nature Genetics examine common variants implicated in more than three dozen conditions, estimating genetic effect similarities across ancestry tracts in admixed individuals.

Sick Newborns Selected for WGS With Automated Pipeline

Researchers successfully prioritized infants with potential Mendelian conditions for whole-genome sequencing or rapid whole-genome sequencing, as they report in Genome Medicine.