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New Product Watch: Nov 30, 2010

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Agilent Technologies last week launched GeneSpring GX 11.5, an expansion of its bioinformatics software.

GeneSpring GX 11.5 now interprets exon microarray, proteomics, and metabolomics experiments together, using a familiar interface, the company said. GeneSpring GX continues to support applications for gene expression analysis, genomic copy number analysis, genome-wide association analysis, and transcriptomics data analysis.

GeneSpring GX 11.5 was developed in conjunction with Strand Scientific Intelligence and is powered by Strand's Avadis platform. The new software also adds advanced data management functions such as a comprehensive backup utility and an enhanced data-migration tool, Agilent said. It includes integration with GeneGo's MetaCore pathway analysis tool, giving users the ability to combine statistical analysis in GeneSpring with MetaCore's strengths in pathway analysis.


Cellix this week launched its Vena4Y and the Vena4Y2 biochips for thrombosis and atherosclerosis research, including the study of platelet adhesion, aggregation and thrombi formation.

According to the Irish firm, its platform integrates flow-based cell adhesion assays with branching microchannels that mimic human capillaries. The biochips allow for the precise control of microliter volumes of biochemical samples and reagents, it said.

The Scan

Team Tracks Down Potential Blood Plasma Markers Linked to Heart Failure in Atrial Fibrillation Patients

Researchers in BMC Genomics found 10 differentially expressed proteins or metabolites that marked atrial fibrillation with heart failure cases.

Study Points to Synonymous Mutation Effects on E. Coli Enzyme Activity

Researchers in Nature Chemistry saw signs of enzyme activity shifts in the presence of synonymous mutations in a multiscale modeling analysis of three Escherichia coli genes.

Team Outlines Paternal Sample-Free Single-Gene Approach for Non-Invasive Prenatal Screening

With data for nearly 9,200 pregnant individuals, researchers in Genetics in Medicine demonstrate the feasibility of their carrier screening and reflex single-gene non-invasive prenatal screening approach.

Germline-Targeting HIV Vaccine Shows Promise in Phase I Trial

A National Institutes of Health-led team reports in Science that a broadly neutralizing antibody HIV vaccine induced bnAb precursors in 97 percent of those given the vaccine.