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New Product Watch: Nov 9, 2010


Illumina last week introduced its Infinium HD FFPE Sample Solution, a reagents kit and protocol that allows its microarray customers to obtain high-quality genotype calls from degraded formalin-fixed, paraffin-embedded samples.

Using a PCR-based assay to identify recoverable samples, Illumina customers will be able to then use the firm's kit to restore those samples that pass a quality-control test, and prepare them for whole-genome analysis on its 12-sample CytoSNP or OmniExpress BeadChips.

According to Illumina, the new kit consists of four reagents and can be purchased separately from its arrays. The restoration workflow takes on average four hours. Illumina expects to begin shipping the kit in the first quarter of 2011.

BioNanomatrix last week introduced its NanoAnalyzer 1000 System for single-molecule analysis.

The system includes the firm's nanochannel chips, instrumentation for high-resolution, multi-color fluorescent imaging with onboard control and analysis software, and reagents for performing catalog and custom applications.

According to the Philadelphia-based company, targeted applications include DNA sample quality assessment, DNA damage assessment, sequence assembly, and structural variation analysis.

BioNanomatrix expects to begin shipment of the NanoAnalyzer 1000 next year.

SurModics recently began selling its Tridia EP epoxy in vitro diagnostic surface coating for glass slides and 96-well plates.

The Tridia EP coating contains an epoxide reactive group for binding amine-modified nucleic acids via the terminal amine. It also binds non-modified nucleic acids via the exocyclic amine groups of the bases and through the hydroxyl groups of the sugar phosphate backbone.

According to the Eden Prairie, Minn.-based firm, applications that can be performed on Tridia EP include DNA methylation studies, SNP analysis, array comparative genomic hybridization, ligand-receptor profiling, and peptide arrays.

The US Food and Drug Administration's National Center for Toxicological Research has launched SNPTrack, a genetic data management, analysis, and interpretation tool.

Developed at NCTR's Center for Bioinformatics, SNPTrack allows users to manage, analyze, and interpret pharmacogenetic data. It includes tree-structured study data view and management; text-based importing and exporting of study data including SNP panel annotation, genotypes, and phenotypes; analysis and visualization capabilities; and links to functional data.

SNPTrack is available here.

The Scan

Tens of Millions Saved

The Associated Press writes that vaccines against COVID-19 saved an estimated 20 million lives in their first year.

Supersized Bacterium

NPR reports that researchers have found and characterized a bacterium that is visible to the naked eye.

Also Subvariants

Moderna says its bivalent SARS-CoV-2 vaccine leads to a strong immune response against Omicron subvariants, the Wall Street Journal reports.

Science Papers Present Gene-Edited Mouse Models of Liver Cancer, Hürthle Cell Carcinoma Analysis

In Science this week: a collection of mouse models of primary liver cancer, and more.