Agilent Technologies last week launched its SurePrint G3 Human CGH+SNP microarray platform for the analysis of chromosomal copy number changes and copy-neutral aberrations.
The system allows researchers to study the genetic basis of developmental disorders as well as many cancers, Agilent said. The company also claims the platform can detect loss of heterozygosity/uniparental disomy with between 5 and 10-megabase resolution.
Agilent's SurePrint G3 CGH+SNP arrays are available in both catalog and custom designs. Custom arrays can be designed in eArray, its online application, or eArray XD, the desktop version.
The catalog SurePrint CGH+SNP 4x180K and 2x400K microarrays both measure approximately 60,000 SNPs. The approximately 120,000 CGH probes on the catalog 4x180K arrays consist of the International Standards for Cytogenomic Arrays Consortium's entire 8x60K version probe set and an additional 60,000 backbone probes, Agilent said. The approximately 300,000 CGH probes on the catalog 2x400K array are gene- and exon-biased, focusing coverage on the most important regions of the genome, the firm said.
Agilent said its Genomic Workbench software can be used to determine copy number changes using CGH probes, to measure allele-specific copy numbers of SNP probes, and to locate regions of LOH/UPD. The software enables concurrent analysis of CGH and SNP data alongside quality control metrics, the company added.
Representatives from Agilent spoke with BioArray News about the new platorm last month (BAN 9/14/2010).
Gentel Biosciences this week launched its APiX Simian Pathogen Array platform. The product includes antigen arrays and chromogenic-based detection kits suitable for screening for specific antibodies to pathogens in the sera of non-human primates.
The new offering is "ideal for colony managers to routinely monitor the ... status of their animals, to maintain high standards of animal and caretaker health and to provide confidence in the integrity of studies using these animals," President and CEO Alex Vodenlich said in a statement.
According to Madison, Wis.-based Gentel, the APiX Simian Pathogen Array is the first of several planned viral antigen arrays for screening specific pathogen-free, non-human primate colonies to ensure virus-free status. The product includes Gentel's APiX View Detection-Simian Pathogen Reagent Kit, which is compatible with the firm's chromogenic detection system and is aligned with its Proteomics Multi-System and AthenaQuant analysis software.
BioArray News spoke with Gentel about the APiX Simian Pathogen Array in August (BAN 8/24/2010).