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New Product Watch: Mar 16, 2010


Illumina this week launched its HumanOmniExpress+ Custom BeadChip. The new array is an enhancement to its OmniExpress BeadChip that allows for the addition of up to 200,000 custom variants to enable customers to survey more than 900,000 variants per sample.

Using the iScan System and an eight-sample array format, Illumina said customers who use the OmniExpress+ can process more than 900 samples per week.

BioDiscovery this week launched Nexus Expression version 2 for gene expression analysis. Nexus Expression provides a software interface for using gene expression results to associate sample attributes with gene annotations and biological processes.

New features in version 2 enable users to load data with a one-click tool and to find relevant biological information, the company said. The software also includes a library of pathways and gene sets to identify the biological implications of differential gene regulation. Another new feature facilitates data loading from array manufacturers' software with a new plug-in for Illumina's software as well as support for CEL files and annotation files from Affymetrix arrays.

The Scan

Germline-Targeting HIV Vaccine Shows Promise in Phase I Trial

A National Institutes of Health-led team reports in Science that a broadly neutralizing antibody HIV vaccine induced bnAb precursors in 97 percent of those given the vaccine.

Study Uncovers Genetic Mutation in Childhood Glaucoma

A study in the Journal of Clinical Investigation ties a heterozygous missense variant in thrombospondin 1 to childhood glaucoma.

Gene Co-Expression Database for Humans, Model Organisms Gets Update

GeneFriends has been updated to include gene and transcript co-expression networks based on RNA-seq data from 46,475 human and 34,322 mouse samples, a new paper in Nucleic Acids Research says.

New Study Investigates Genomics of Fanconi Anemia Repair Pathway in Cancer

A Rockefeller University team reports in Nature that FA repair deficiency leads to structural variants that can contribute to genomic instability.