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New Product Watch: Mar 9, 2010


Fluidigm this week launched 5-kilobase and 10-kilobase long-range PCR protocols for its Access Array System. Access Array, launched last year, enables users to amplify up to 48 samples per array for use in targeted resequencing applications. The availability of long-range PCR will allow researchers to enrich more sequence per sample, Fluidigm said.

The company said that the new protocols offer the capability to enrich up to 240 kb per sample and 11.5 megabases per array, or 480 kb and 23 Mb per array, respectively, from 48 samples at a time.

The output generated by Fluidigm's Access Array system can be used in several high-throughput sequencers, including the Roche 454 FLX, Illumina Genome Analyzer II, and Life Technologies SOLiD 4.

SciGene this week released new methods for its ArrayPrep Target Preparation System that support the automated preparation of labeled gDNA using Agilent Technologies or Roche NimbleGen reagent kits.

The company also announced that its Little Dipper Software now supports both Agilent and Roche NimbleGen platforms.

Epigentek this week launched its BisulFlash DNA Modification Kit, which it claims can convert unmethylated cytosine into uracil in around 30 minutes.

The converted DNA eluate can be obtained for use in mutagenically separated PCR, real time MS-PCR, methylation microarray, and methylation sequencing and pyrosequencing applications, the company said.

The Scan

Octopus Brain Complexity Linked to MicroRNA Expansions

Investigators saw microRNA gene expansions coinciding with complex brains when they analyzed certain cephalopod transcriptomes, as they report in Science Advances.

Study Tracks Outcomes in Children Born to Zika Virus-Infected Mothers

By following pregnancy outcomes for women with RT-PCR-confirmed Zika virus infections, researchers saw in Lancet Regional Health congenital abnormalities in roughly one-third of live-born children.

Team Presents Benchmark Study of RNA Classification Tools

With more than 135 transcriptomic datasets, researchers tested two dozen coding and non-coding RNA classification tools, establishing a set of potentially misclassified transcripts, as they report in Nucleic Acids Research.

Breast Cancer Risk Related to Pathogenic BRCA1 Mutation May Be Modified by Repeats

Several variable number tandem repeats appear to impact breast cancer risk and age at diagnosis in almost 350 individuals carrying a risky Ashkenazi Jewish BRCA1 founder mutation.