Skip to main content
Premium Trial:

Request an Annual Quote

New Product Watch: Feb 16, 2010


Kinexus Bioinformatics last week launched its protein kinase microarray with 200 recombinant human protein kinases for screening. The microarray can be used for drug target counter-screening, to identify novel kinase substrates, establish kinase antibody specificities, and for the discovery and testing of protein kinase-protein and protein kinase-compound interactions, according to the Vancouver, Canada-based firm.

All compounds selected using the new array can be further validated for direct activity effects in vitro with Kinexus' kinase-inhibitor profiling services, the firm added. Customers can also use the company's Kinex 800 antibody microarray services, to define endogenous physiological substrates of target kinases in order to measure the effects of drug leads in vivo in cultured cells and tissues from the new protein array platform (see BAN 9/1/2009).

BioDiscovery last week launched the fifth version of its Nexus Copy Number software for DNA copy number analysis of microarray derived data.

The new version includes a cloud-based database, called Nexus DB, for secure storage, cross project queries, and global collaboration; and a survival predictive power tool to identify aberrant regions of the genome that have a high degree of survival prediction accuracy. Nexus Copy Number can also now directly import from and export data to the UCSC Genome Browser, display probe-level data for multiple samples in a single display, support Affymetrix CYCHP files, and incorporate methylation data, the company said.

The Scan

Study Examines Insights Gained by Adjunct Trio RNA Sequencing in Complex Pediatric Disease Cases

Researchers in AJHG explore the diagnostic utility of adding parent-child RNA-seq to genome sequencing in dozens of families with complex, undiagnosed genetic disease.

Clinical Genomic Lab Survey Looks at Workforce Needs

Investigators use a survey approach in Genetics in Medicine Open to assess technologist applications, retention, and workforce gaps at molecular genetics and clinical cytogenetics labs in the US.

Study Considers Gene Regulatory Features Available by Sequence-Based Modeling

Investigators in Genome Biology set sequence-based models against observational and perturbation assay data, finding distal enhancer models lag behind promoter predictions.

Genetic Testing Approach Explores Origins of Blastocyst Aneuploidy

Investigators in AJHG distinguish between aneuploidy events related to meiotic missegregation in haploid cells and those involving post-zygotic mitotic errors and mosaicism.