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New Product Watch: Oct 20, 2009


LC Sciences this week began offering probe content from the Plant MicroRNA Database for its microRNA microarray customers.

The PMRD integrates available plant miRNA data deposited in other public databases, gleaned from the recent literature, and data generated by the database organizers. It is available here.

LC Sciences' miRNA microarrays are available on its µParaflo microfluidics on-chip synthesis platform. In total, there are 8,433 miRNAs collected from 121 plant species in PMRD — including model plants and crops such as Arabidopsis, rice, wheat, soybean, maize, sorghum, and barley — on the chip.

TIBCO Software and Integromics this week launched Integromics Biomarker Discovery 2.0 for TIBCO Spotfire, a new data analysis package that provides methods for normalization, pattern detection, treatment comparison, and functional analysis for scientists analyzing genomic expression data.

The offering enables researchers to examine the expression and annotation dimensions of their data and perform a variety of numerical analyses, the firms said.

The Scan

Positive Framing of Genetic Studies Can Spark Mistrust Among Underrepresented Groups

Researchers in Human Genetics and Genomics Advances report that how researchers describe genomic studies may alienate potential participants.

Small Study of Gene Editing to Treat Sickle Cell Disease

In a Novartis-sponsored study in the New England Journal of Medicine, researchers found that a CRISPR-Cas9-based treatment targeting promoters of genes encoding fetal hemoglobin could reduce disease symptoms.

Gut Microbiome Changes Appear in Infants Before They Develop Eczema, Study Finds

Researchers report in mSystems that infants experienced an enrichment in Clostridium sensu stricto 1 and Finegoldia and a depletion of Bacteroides before developing eczema.

Acute Myeloid Leukemia Treatment Specificity Enhanced With Stem Cell Editing

A study in Nature suggests epitope editing in donor stem cells prior to bone marrow transplants can stave off toxicity when targeting acute myeloid leukemia with immunotherapy.