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New Product Watch: Jan 20, 2009

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GE Healthcare last week launched illustra triplePrep, a kit for the isolation of genomic DNA, RNA and total denatured protein from a single sample.

The product combines two spin columns and six optimized buffers for use with mammalian cell culture or animal tissue. High quality and yield DNA, RNA, and protein can be successfully isolated from a range of tissue types such as liver, kidney, spleen, brain, lung, and intestine, and the cell lines HeLa, NIH-3T3, CHO-K1, and HEK-293, GE claimed.

The isolated gDNA, total RNA, and total denatured proteins are suitable for various genomic and proteomic applications such as sequencing, array comparative genomic hybridization, and array-based gene expression, GE said.

The Scan

Lung Cancer Response to Checkpoint Inhibitors Reflected in Circulating Tumor DNA

In non-small cell lung cancer patients, researchers find in JCO Precision Oncology that survival benefits after immune checkpoint blockade coincide with a dip in ctDNA levels.

Study Reviews Family, Provider Responses to Rapid Whole-Genome Sequencing Follow-up

Investigators identified in the European Journal of Human Genetics variable follow-up practices after rapid whole-genome sequencing.

BMI-Related Variants Show Age-Related Stability in UK Biobank Participants

Researchers followed body mass index variant stability with genomic structural equation modeling and genome-wide association studies of 40- to 72-year olds in PLOS Genetics.

Genome Sequences Reveal Range Mutations in Induced Pluripotent Stem Cells

Researchers in Nature Genetics detect somatic mutation variation across iPSCs generated from blood or skin fibroblast cell sources, along with selection for BCOR gene mutations.