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New Product Watch: Mar 24, 2009

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Ambry Genetics this week began offering sequence capture for the Illumina Genome Analyzer II or Roche 454 Life Sciences GS FLX Titanium second-generation sequencing platforms.

The Aliso Viejo, Calif.-based CLIA-compliant lab offers the application using custom 385K or pre-designed 2.1M high-density arrays available through Roche NimbleGen. Sequencing can be done in-house at Ambry on the Illumina GA II, or returned to the customer for sequencing on their platform, the company said.

The Scan

Study Examines Insights Gained by Adjunct Trio RNA Sequencing in Complex Pediatric Disease Cases

Researchers in AJHG explore the diagnostic utility of adding parent-child RNA-seq to genome sequencing in dozens of families with complex, undiagnosed genetic disease.

Clinical Genomic Lab Survey Looks at Workforce Needs

Investigators use a survey approach in Genetics in Medicine Open to assess technologist applications, retention, and workforce gaps at molecular genetics and clinical cytogenetics labs in the US.

Study Considers Gene Regulatory Features Available by Sequence-Based Modeling

Investigators in Genome Biology set sequence-based models against observational and perturbation assay data, finding distal enhancer models lag behind promoter predictions.

Genetic Testing Approach Explores Origins of Blastocyst Aneuploidy

Investigators in AJHG distinguish between aneuploidy events related to meiotic missegregation in haploid cells and those involving post-zygotic mitotic errors and mosaicism.