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New Product Watch: Jan 13, 2009


Illumina this week launched its Infinium HD iSelect Custom Genotyping solution. The product enables customers to screen SNPs ranging from 3,000 to 200,000 in focused genotyping studies for both human and non-human species.

Illumina also launched Infinium HD iSelect arrays for agricultural biotechnology clients. According to Illumina, the 12-sample OvineSNP50 and PorcineSNP60 BeadChips enable researchers to detect genome-wide genetic variation in any breed of sheep or pig.

Illumina also has iSelect SNP arrays available for bovine, equine, and canine studies.

Agilent Technologies this week announced the release of its eArray 5.4 online microarray design tool, which now enables users to design custom microRNA microarrays.

Researchers can use Agilent's pre-designed human, mouse or rat miRNA probes, or access miRNA sequences for all 87 species in Sanger 12.0 in the designs of their miRNA microarrays, the company said.

Agilent also announced updates to its human and mouse miRNA microarrays, which contain the latest probes from Sanger miRBASE 12.0 database. These arrays contain 15,000 features and are printed eight arrays per slide.

Pathwork Diagnostics this week launched a version of its Tissue of Origin Test that is capable of analyzing formalin-fixed, paraffin-embedded tissue specimens. The new test is available as a service through the Pathwork's CLIA-compliant laboratory.

The Tissue of Origin Test runs on the Affymetrix GeneChip platform and measures the expression pattern of more than 1,500 genes in tumors with an uncertain origin and compares it to expression patterns of a panel of 15 known tumor types, representing 90 percent of all solid tumors and 58 morphologies overall.

Pathwork said it will seek US Food and Drug Administration clearance for the FFPE version of the Tissue of Origin Test in an in vitro diagnostic kit format so that pathologists can run the test in their own clinical laboratories.

Scienion and Matrical Bioscience this week launched SciSwifter, a device for dispensing in 96, 384, and 1536 microplates.

SciSwifter can dispense up to 16 different substances in parallel into various multi-well plate formats, can operate as a stand-alone device, and includes integrated touch-screen controls, robotics shuttle, and external software API for integration into automated robotics platforms.

Scienion and Matrical plan to co-market the tool.

The Scan

New Study Highlights Role of Genetics in ADHD

Researchers report in Nature Genetics on differences in genetic architecture between ADHD affecting children versus ADHD that persists into adulthood or is diagnosed in adults.

Study Highlights Pitfall of Large Gene Panels in Clinical Genomic Analysis

An analysis in Genetics in Medicine finds that as gene panels get larger, there is an increased chance of uncovering benign candidate variants.

Single-Cell Atlas of Drosophila Embryogenesis

A new paper in Science presents a single-cell atlas of fruit fly embryonic development over time.

Phage Cocktail Holds Promise for IBD

Researchers uncovered a combination phage therapy that targets Klebsiella pneumonia strains among individuals experiencing inflammatory bowel disease flare ups, as they report in Cell.