A quartet of recent papers authored by geneticists at Birmingham Women's Hospital has shed greater light on the application of chromosomal microarrays in prenatal diagnostics in the UK.

The studies, which appeared in four journals over the past two months, compared array-based testing to conventional karyotyping, compared lower-resolution array platforms with higher-resolution chips, and the authors discussed issues related to variants of unclear significance, as well as patient counseling.

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