Skip to main content
Premium Trial:

Request an Annual Quote

NCI Awards Contract to PGXL for CTC Research

NEW YORK (GenomeWeb News) – PGXL Technologies today said that it has been awarded a $300,000 contract from the National Cancer Institute to advance research directed at circulating tumor cells for the early detection of cancer.

The Louisville, Ky.-based firm, a sister company to PGXL Laboratories, uses a technology called DEPArray, developed by Silicon Biosystems. The two firms said in April they were collaborating to make the technology available through PGXL.

The DEPArray technology is based on dielectrophoresis for isolating and manipulating cells in a suspension matrix and can be used to investigate the underlying causes of disease, disease progression, and the basis of drug resistance and efficacy.

PGXL said today that it and Silicon Biosystems are developing a method to identify and isolate CTCs "that are invisible to conventional technology." Kevin Goudy heads the PGXL team that will carry out the work on the NCI contract, which is one of four awarded by the institute to expand the types of detectable CTCs.

The Scan

Germline-Targeting HIV Vaccine Shows Promise in Phase I Trial

A National Institutes of Health-led team reports in Science that a broadly neutralizing antibody HIV vaccine induced bnAb precursors in 97 percent of those given the vaccine.

Study Uncovers Genetic Mutation in Childhood Glaucoma

A study in the Journal of Clinical Investigation ties a heterozygous missense variant in thrombospondin 1 to childhood glaucoma.

Gene Co-Expression Database for Humans, Model Organisms Gets Update

GeneFriends has been updated to include gene and transcript co-expression networks based on RNA-seq data from 46,475 human and 34,322 mouse samples, a new paper in Nucleic Acids Research says.

New Study Investigates Genomics of Fanconi Anemia Repair Pathway in Cancer

A Rockefeller University team reports in Nature that FA repair deficiency leads to structural variants that can contribute to genomic instability.