Millennium Pharmaceuticals and Signature Biosciences | GenomeWeb

Millennium Pharmaceuticals has received US Patent Number 6,342,351 “Methods and compositions for diagnosing and treating chromosome-18p related disorders.” The patent covers methods for diagnosis, genetic testing, and prognosis of bipolar affective disorder (manic depression). According to the invention, testing for the HKNG1 gene can be used as a diagnostic marker for bipolar affective disorder, as well as schizophrenia, attention deficit disorder, schizoaffective disorder, and unipolar affective disorders.

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