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Mendelbase, Gyrolab MALDI SP1, Gyrolab Workstation

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Array Genetics, a Newtown, Conn. bioinformatics company, has developed Mendelbase, a database of functional genomic information designed to categorize genes identified through DNA microarray screening. The database’s creator, W. Scott Argraves, is looking for scientists to provide to the database functional information on proteins. The website for this database is: http://www.arraygenetics.com/about_mendelBase.html.

 

Gyros of Uppsala, Sweden, has debuted its Gyrolab MALDI SP1 and Gyrolab Workstation, the first products based on its compact-disk format microfluidic technology. Gyrolab MALDI SP1 is a microfluidic sample preparation device for MALDI mass spectrometry. The device concentrates and purifies protein digests, processing 96 at a time, then crystallizes them onto MALDI target areas of the compact disk. Gyrolab Workstation directs this process, transferring samples and reagents onto the Gyrolab MALDI SP1, then moving them through the channels by spinning the compact disk substrate.

The Scan

Enzyme Involved in Lipid Metabolism Linked to Mutational Signatures

In Nature Genetics, a Wellcome Sanger Institute-led team found that APOBEC1 may contribute to the development of the SBS2 and SBS13 mutational signatures in the small intestine.

Family Genetic Risk Score Linked to Diagnostic Trajectory in Psychiatric Disorders

Researchers in JAMA Psychiatry find ties between high or low family genetic risk scores and diagnostic stability or change in four major psychiatric disorders over time.

Study Questions Existence of Fetal Microbiome

A study appearing in Nature this week suggests that the reported fetal microbiome might be the result of sample contamination.

Fruit Fly Study Explores Gut Microbiome Effects on Circadian Rhythm

With gut microbiome and gene expression experiments, researchers in PNAS see signs that the microbiome contributes to circadian rhythm synchronicity and stability in fruit flies.