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Media Cybernetics, Stressgen Biotechnologies, Agilent Technologies

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Media Cybernetics of Silver Spring, Md., earned US Patent No. 6,498,863, “Method, system, and product for analyzing a digitized image of an array to create an image of a grid overlay.” The patent covers a system for analyzing a digitized image of an array to create an image of a grid overlay. The method includes finding the center of each object on the array, determining a standard shape and size for the objects, and creating a final image of the grid overlay.

Stressgen Biotechnologies of Victoria, Calif., was awarded US Patent No. 6,497,880, “Heat shock genes and proteins from Neisseria meningitidis, Candida glabrata and Aspergillus fumigatus.” The patent covers methods for isolating nucleic acid molecules and creating a biochip array comprised of a substrate to which either oligonucleotides, polypeptides or antibodies may be bound.

Agilent Technologies of Palo Alto, Calif., earned US Patent No. 6,495,016, “Microfluidic microchip with integrated substance injection.” The technology includes a channel structure connected to a separation channel. Pulse-shaped substance volume sequences are injected into the separation channel. The signal-to-noise ratio of the measurement results is improved by generating substance volume sequences on the basis of pseudo-randomly scattered binary digit sequences, and by a cross-correlation analysis of spectra.

 

The Scan

Self-Reported Hearing Loss in Older Adults Begins Very Early in Life, Study Says

A JAMA Otolaryngology — Head & Neck Surgery study says polygenic risk scores associated with hearing loss in older adults is also associated with hearing decline in younger groups.

Genome-Wide Analysis Sheds Light on Genetics of ADHD

A genome-wide association study meta-analysis of attention-deficit hyperactivity disorder appearing in Nature Genetics links 76 genes to risk of having the disorder.

MicroRNA Cotargeting Linked to Lupus

A mouse-based study appearing in BMC Biology implicates two microRNAs with overlapping target sites in lupus.

Enzyme Involved in Lipid Metabolism Linked to Mutational Signatures

In Nature Genetics, a Wellcome Sanger Institute-led team found that APOBEC1 may contribute to the development of the SBS2 and SBS13 mutational signatures in the small intestine.