Linden Technologies, Clontech Laboratories, Phylos, Molecular Dynamics | GenomeWeb

Linden Technologies of Woburn, Mass., has received US Patent No. 6,489,466 , “C-3' protected monomeric nucleotides and synthesis of oligonucleotides on solid support.” The invention covers modified nucleotide primers that are anchored to a substrate through a linking group, and used in synthesis and screening of oligonucleotide arrays. The C-5’ end of this nucleotide is modified to be tethered to the linking group, and the C-3’ end is not, so other nucleotides can be added to the primer.

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