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LC Sciences, NuGen Technologies, Hamilton Company

LC Sciences said recently that it has updated its catalog and custom microRNA arrays to reflect the content of miRBase version 12.0, the database of miRNA sequences hosted by the Wellcome Trust Sanger Institute and the University of Manchester.
The Houston, Tex.-based company said that many of the new additions to miRBase 12.0 were identified using its µParaflo microarray platform.

NuGen Technologies and the Hamilton Company last week launched an automated, target-preparation approach for processing large sets of clinical samples for global gene expression analysis.
The approach combines NuGen's Ovation Systems with the Hamilton Microlab Starlet bench-top liquid handling system to increase throughput and improve workflow for small RNA samples commonly used in clinical signature and biomarker discovery.
Together, the two systems offer a full range of target preparation functions, including RNA amplification, purification, fragmentation, and labeling for gene expression analysis using Affymetrix GeneChip and other platforms, NuGen and Hamilton said.

The Scan

Germline-Targeting HIV Vaccine Shows Promise in Phase I Trial

A National Institutes of Health-led team reports in Science that a broadly neutralizing antibody HIV vaccine induced bnAb precursors in 97 percent of those given the vaccine.

Study Uncovers Genetic Mutation in Childhood Glaucoma

A study in the Journal of Clinical Investigation ties a heterozygous missense variant in thrombospondin 1 to childhood glaucoma.

Gene Co-Expression Database for Humans, Model Organisms Gets Update

GeneFriends has been updated to include gene and transcript co-expression networks based on RNA-seq data from 46,475 human and 34,322 mouse samples, a new paper in Nucleic Acids Research says.

New Study Investigates Genomics of Fanconi Anemia Repair Pathway in Cancer

A Rockefeller University team reports in Nature that FA repair deficiency leads to structural variants that can contribute to genomic instability.