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Large Scale Biology, Sainsbury Laboratory, Denise Gilbert


Large Scale Biology has appointed Professor David Baulcombe of the Sainsbury Laboratory, in Norwich, UK, to its scientific advisory board. Under the multi-year arrangement, the company will also sponsor three years of research in Baulcombe''''s lab on viral-derived gene silencing and overexpression technologies.

LSBC intends to commercialize the technology that Baulcombe, a leading scientist in the area of post-transcriptional gene silencing or RNA interference, has developed. This mechanism has potential applications in determining gene function in mammals and higher species.


Denise Gilbert, who left her position as Incyte''''s executive vice president and chief financial officer in late 1999 to bicycle around the world, has been appointed CEO of Entigen. At the Sunnyvale, Calif.-based company, Gilbert is expected to execute the strategy of finding new applications for its ADAAPT data aggregation, access, and analysis platform beyond bioinformatics.

Gilbert''''s other business experience includes a term as vice president and chief financial officer at Affymax, where she participated in its $550 million acquisition by Glaxo-Wellcome. Before that, Gilbert spent seven years as a biotechnology analyst on Wall Street. Gilbert has a PhD in Cell and Developmental Biology from Harvard.

The Scan

Renewed Gain-of-Function Worries

The New York Times writes that the pandemic is renewing concerns about gain-of-function research.

Who's Getting the Patents?

A trio of researchers has analyzed gender trends in biomedical patents issued between 1976 and 2010 in the US, New Scientist reports.

Other Uses

CBS Sunday Morning looks at how mRNA vaccine technology could be applied beyond SARS-CoV-2.

PLOS Papers Present Analysis of Cervicovaginal Microbiome, Glycosylation in Model Archaea, More

In PLOS this week: functional potential of the cervicovaginal microbiome, glycosylation patterns in model archaea, and more.