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Large Scale Biology, Sainsbury Laboratory, Denise Gilbert


Large Scale Biology has appointed Professor David Baulcombe of the Sainsbury Laboratory, in Norwich, UK, to its scientific advisory board. Under the multi-year arrangement, the company will also sponsor three years of research in Baulcombe''''s lab on viral-derived gene silencing and overexpression technologies.

LSBC intends to commercialize the technology that Baulcombe, a leading scientist in the area of post-transcriptional gene silencing or RNA interference, has developed. This mechanism has potential applications in determining gene function in mammals and higher species.


Denise Gilbert, who left her position as Incyte''''s executive vice president and chief financial officer in late 1999 to bicycle around the world, has been appointed CEO of Entigen. At the Sunnyvale, Calif.-based company, Gilbert is expected to execute the strategy of finding new applications for its ADAAPT data aggregation, access, and analysis platform beyond bioinformatics.

Gilbert''''s other business experience includes a term as vice president and chief financial officer at Affymax, where she participated in its $550 million acquisition by Glaxo-Wellcome. Before that, Gilbert spent seven years as a biotechnology analyst on Wall Street. Gilbert has a PhD in Cell and Developmental Biology from Harvard.

The Scan

Alzheimer's Risk Gene Among Women

CNN reports that researchers have found that variants in MGMT contribute to Alzheimer's disease risk among women but not men.

Still Hanging Around

The Guardian writes that persistent pockets of SARS-CoV-2 in the body could contribute to long COVID.

Through a Little Spit

Enteric viruses like norovirus may also be transmitted through saliva, not just the fecal-oral route, according to New Scientist.

Nature Papers Present Method to Detect Full Transcriptome, Viruses Infecting Asgard Archaea, More

In Nature this week: VASA-seq approach to detect full transcriptome, analysis of viruses infecting Asgard archaea, and more.