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John West, John Stuelpnagel, Tristan Orpin, Christian Henry, Matt Posard, Omead Ostadan, Blaine Bowman, Roy Whitfield

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Illumina has made several management changes in the wake of its acquisition of Solexa last month. John West, the former CEO of Solexa, has joined Illumina as senior vice president and general manager of the sequencing business; John Stuelpnagel, Illumina’s COO, will now also serve as general manager of the company’s microarray business; Tristan Orpin, Illumina’s vice president of sales, has been promoted to senior vice president in charge of all commercial operations; Christian Henry, vice president and CFO, has been promoted to senior vice president and CFO and has assumed the additional responsibility of investor relations; Matt Posard, vice president of marketing, is now vice president of sales; while Omead Ostadan, formerly vice president of marketing at Solexa, will replace Posard as vice president of marketing at Illumina. In addition, Solexa directors Blaine Bowman and Roy Whitfield have joined Illumina’s board.

The Scan

Myotonic Dystrophy Repeat Detected in Family Genome Sequencing Analysis

While sequencing individuals from a multi-generation family, researchers identified a myotonic dystrophy type 2-related short tandem repeat in the European Journal of Human Genetics.

TB Resistance Insights Gleaned From Genome Sequence, Antimicrobial Response Assays

Researchers in PLOS Biology explore M. tuberculosis resistance with a combination of sequencing and assays looking at the minimum inhibitory concentrations of 13 drugs.

Mendelian Disease Genes Prioritized Using Tissue-Specific Expression Clues

Mendelian gene candidates could be flagged for further functional analyses based on tissue-specific transcriptome and proteome profiles, a new Journal of Human Genetics paper says.

Single-Cell Sequencing Points to Embryo Mosaicism

Mosaicism may affect preimplantation genetic tests for aneuploidy, a single-cell sequencing-based analysis of almost three dozen embryos in PLOS Genetics finds.