Columbia University of New York has received US Patent No. 8,133,492, "Pneumococcus polysaccharide-related vaccines." Nitrocellulose-based or hydrogel-based microarrays and methods of making them are claimed. The arrays can be used to detect the presence of one or more agents in a sample; to determine the amount of agents in a sample; to determine whether a subject is afflicted with a disorder; and to determine whether an agent known to specifically bind to a first compound also specifically binds to a second compound.

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