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IP Roundup: Ventana Medical Systems, Micronics, Agilent Technologies

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Ventana Medical Systems, a member of the Roche Group, has received US Patent No. 8,329,401, "Enzyme-catalyzed metal deposition for the enhanced detection of analytes of interest." The patent provides methods for detecting an analyte of interest in situ, by immunoassay, or by array-based hybridization by binding an enzyme-labeled conjugate molecule to an analyte of interest in the presence of a redox-inactive reductive species and a soluble metal ion. According to the patent, the enzyme catalyzes the conversion of the inactive reductive species to an active reducing agent, which in turn reduces the metal ion to a metal atom, providing an enhanced means of detecting the analyte via metal deposition.


Micronics of Redmond, Wash., has received US Patent No. 8,329,453, "Portable high gain fluorescence detection system." The patent describes a microprocessor-controlled instrument for fluorometric assays in liquid samples. According to the patent, the system can support applications that include molecular biological assays based on PCR amplification of target nucleic acids and fluorometric assays, some of which require temperature control during detection.


Agilent Technologies of Santa Clara, Calif., has received US Patent No. 8,332,737, "Instrument control system and methods." The patent claims methods, systems and computer-readable media for controlling an instrument, including but not limited to a microarray scanner, in communication with a host computer. According to the patent, the operations of the instrument are controlled via a controller embedded in the instrument. A complete status packet is sent to a host computer from the embedded controller and, periodically, the embedded controller repeats the sending of a complete status packet to the host computer, where the status values in the complete status packet are updated with each iteration of sending a complete status packet.

The Scan

To Boost Rapid Testing

The Washington Post writes that new US programs aim to boost the availability of rapid at-home SARS-CoV-2 tests.

PNAS Papers on Strawberry Evolution, Cell Cycle Regulators, False-Positive Triplex Gene Editing

In PNAS this week: strawberry pan-genome, cell cycle-related roles for MDM2 and MDMX, and more.

Not Immediately Told

The US National Institutes of Health tells lawmakers that one of its grantees did not immediately report that it had developed a more infectious coronavirus, Science says.

Seems Effective in Kids

The Associated Press reports that the Pfizer-BioNTech SARS-CoV-2 vaccine for children appears to be highly effective at preventing symptomatic disease.