Ventana Medical Systems, a member of the Roche Group, has received US Patent No. 8,329,401, "Enzyme-catalyzed metal deposition for the enhanced detection of analytes of interest." The patent provides methods for detecting an analyte of interest in situ, by immunoassay, or by array-based hybridization by binding an enzyme-labeled conjugate molecule to an analyte of interest in the presence of a redox-inactive reductive species and a soluble metal ion.

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