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IP Roundup: UCF, Illumina, Roche, Dart Neuroscience, Others Win US Patents

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The University of Central Florida Research Foundation has been awarded US Patent No. 8,859,266, "Binary probe system for sensitive detection of target analytes."

Yuliva Gerasimova and Dmitry Kolpashchikov are named as the inventors.


The Centre National de la Recherche Scientifique, Universite Paul Sabatier Toulouse III, and Institut Claudius Regaud have been awarded US Patent No. 8,865,408, "Signature for the diagnosis of cancer aggressiveness and genetic instability."

Christophe Cazaux, Jean-Sebastien Hoffmann, Jean-Christophe Bourdon, Alice Machado Da Silva, and Henri Roche are named as the inventors.


Illumina has been awarded US Patent No. 8,867,029, "Systems for methods of facilitating focusing of an optical scanner."

Wenyi Feng is named as the inventor.


Roche Molecular Systems has been awarded US Patent No. 8,868,393, "Algorithms for classification of disease subtypes and for prognosis with gene expression profiling."

Wei-Min Lin is named as the inventor.


Dart Neuroscience has been awarded US Patent No. 8,868,349, "Methods, systems, and products for quantitatively measuring the degree of concordance between or among microarray probe level data sets."

Philip Cheung, Timothy Tully, Humberto Ortiz-Zuazaga, and Oscar Moreno are named as the inventors.

The Scan

Machine Learning Helps ID Molecular Mechanisms of Pancreatic Islet Beta Cell Subtypes in Type 2 Diabetes

The approach helps overcome limitations of previous studies that had investigated the molecular mechanisms of pancreatic islet beta cells, the authors write in their Nature Genetics paper.

Culture-Based Methods, Shotgun Sequencing Reveal Transmission of Bifidobacterium Strains From Mothers to Infants

In a Nature Communications study, culture-based approaches along with shotgun sequencing give a better picture of the microbial strains transmitted from mothers to infants.

Microbial Communities Can Help Trees Adapt to Changing Climates

Tree seedlings that were inoculated with microbes from dry, warm, or cold sites could better survive drought, heat, and cold stress, according to a study in Science.

A Combination of Genetics and Environment Causes Cleft Lip

In a study published in Nature Communications, researchers investigate what combination of genetic and environmental factors come into play to cause cleft lip/palate.