The University of Rochester of Rochester, NY, has received US Patent No. 8,450,056, "Arrayed imaging reflectometry (AIR) sensor chip comprising virus-like particles suitable for the detection of antiviral immune responses." The chip consists of a multilayer substrate that hosts virus-like particles or viral-capsid fragments from different viral strains or isolates that are covalently attached at different locations. These particles or fragments contain conformational epitopes that are capable of binding to antiviral antibodies.

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