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IP Roundup: MIT, CSHL, Northwestern University, Wayne State University, Roche NimbleGen

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Title: Method for enhancing current throughput in an electrochemical system.
Patent Number: 8,753,492
Filed: June 17, 2011
Lead Inventor: Sung Hee Ko, Massachusetts Institute of Technology


Title: Method for making populations of defined nucleic acid molecules.
Patent Number: 8,753,811
Filed: Feb. 16, 2012
Lead Inventor: Stephen Friend, Cold Spring Harbor Laboratory


Title: Generation of combinatorial patterns by deliberate tilting of a polymer-pen array.
Patent Number: 8,753,813
Filed: Dec. 2, 2010
Lead Inventor: Chad Mirkin, Northwestern University


Title: Neoepitope detection of disease using protein arrays.
Patent Number: 8,753,822
Filed: June 20, 2011
Lead Inventor: Michael Tainsky, Wayne State University


Title: Multiplexed microarray assembly and method for fabricating a multiplexed microarray.
Patent Number: 8,753,873
Filed: Feb. 15, 2012
Lead Inventor: John Luckey, Roche NimbleGen

The Scan

Positive Framing of Genetic Studies Can Spark Mistrust Among Underrepresented Groups

Researchers in Human Genetics and Genomics Advances report that how researchers describe genomic studies may alienate potential participants.

Small Study of Gene Editing to Treat Sickle Cell Disease

In a Novartis-sponsored study in the New England Journal of Medicine, researchers found that a CRISPR-Cas9-based treatment targeting promoters of genes encoding fetal hemoglobin could reduce disease symptoms.

Gut Microbiome Changes Appear in Infants Before They Develop Eczema, Study Finds

Researchers report in mSystems that infants experienced an enrichment in Clostridium sensu stricto 1 and Finegoldia and a depletion of Bacteroides before developing eczema.

Acute Myeloid Leukemia Treatment Specificity Enhanced With Stem Cell Editing

A study in Nature suggests epitope editing in donor stem cells prior to bone marrow transplants can stave off toxicity when targeting acute myeloid leukemia with immunotherapy.