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IP Roundup: MIT, CSHL, Northwestern University, Wayne State University, Roche NimbleGen


Title: Method for enhancing current throughput in an electrochemical system.
Patent Number: 8,753,492
Filed: June 17, 2011
Lead Inventor: Sung Hee Ko, Massachusetts Institute of Technology

Title: Method for making populations of defined nucleic acid molecules.
Patent Number: 8,753,811
Filed: Feb. 16, 2012
Lead Inventor: Stephen Friend, Cold Spring Harbor Laboratory

Title: Generation of combinatorial patterns by deliberate tilting of a polymer-pen array.
Patent Number: 8,753,813
Filed: Dec. 2, 2010
Lead Inventor: Chad Mirkin, Northwestern University

Title: Neoepitope detection of disease using protein arrays.
Patent Number: 8,753,822
Filed: June 20, 2011
Lead Inventor: Michael Tainsky, Wayne State University

Title: Multiplexed microarray assembly and method for fabricating a multiplexed microarray.
Patent Number: 8,753,873
Filed: Feb. 15, 2012
Lead Inventor: John Luckey, Roche NimbleGen

The Scan

Self-Reported Hearing Loss in Older Adults Begins Very Early in Life, Study Says

A JAMA Otolaryngology — Head & Neck Surgery study says polygenic risk scores associated with hearing loss in older adults is also associated with hearing decline in younger groups.

Genome-Wide Analysis Sheds Light on Genetics of ADHD

A genome-wide association study meta-analysis of attention-deficit hyperactivity disorder appearing in Nature Genetics links 76 genes to risk of having the disorder.

MicroRNA Cotargeting Linked to Lupus

A mouse-based study appearing in BMC Biology implicates two microRNAs with overlapping target sites in lupus.

Enzyme Involved in Lipid Metabolism Linked to Mutational Signatures

In Nature Genetics, a Wellcome Sanger Institute-led team found that APOBEC1 may contribute to the development of the SBS2 and SBS13 mutational signatures in the small intestine.