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IP Roundup: IntegenX, NRCC, Callida Genomics, DNA Chip Research, Illumina, and More


Title: Microfluidic devices with mechanically-sealed diaphragm valves.
Patent Number: 8,763,642
Filed: Feb. 23, 2012
Lead Inventor: Mattias Vangbo, IntegenX

Title: Ultrasensitive detection of target using target-ready particles.
Patent Number: 8,765,369
Filed: July 11, 2008
Lead Inventor: Sebastian Dubus, National Research Council of Canada

Title: Method for sequencing polynucleotides by forming separate fragment mixtures.
Patent Number: 8,765,375
Filed: Aug. 8, 2013
Lead Inventor: Radoje Drmanac, Callida Genomics

Title: Nucleic acid sequence analysis from combined mixtures of amplified fragments.
Patent Number: 8,765,379
Filed: Jan. 31, 2011
Lead Inventor: Radoje Drmanac, Callida Genomics

Title: Genome sequence analysis using tagged amplicons.
Patent Number: 8,765,382
Filed: Aug. 23, 2013
Lead Inventor: Radoje Drmanac, Callida Genomics

Title: Method of elongating DNA through immobilizing primer DNA chains on a substrate, a method of amplifying a DNA chain.
Patent Number: 8,765,417
Filed: Nov. 29, 2005
Lead Inventor: Kenji Kinoshita, DNA Chip Research

Title: Optically encoded particles.
Patent Number: 8,765,484
Filed: Jan. 31, 2003
Lead Inventor: Michael Sailor, University of California

Title: Methods and systems for controlling liquids in multiplex assays.
Patent Number: 8,765,486
Filed: Nov. 20, 2012
Lead Inventor: Chad DeRosier, Illumina

Title: Chip production, hybridization, and data interpretation for antibody and protein microarrays.
Patent Number: 8,765,641
Filed: March 18, 2005
Lead Inventor: Hyesook Kim, Detroit R&D

The Scan

Positive Framing of Genetic Studies Can Spark Mistrust Among Underrepresented Groups

Researchers in Human Genetics and Genomics Advances report that how researchers describe genomic studies may alienate potential participants.

Small Study of Gene Editing to Treat Sickle Cell Disease

In a Novartis-sponsored study in the New England Journal of Medicine, researchers found that a CRISPR-Cas9-based treatment targeting promoters of genes encoding fetal hemoglobin could reduce disease symptoms.

Gut Microbiome Changes Appear in Infants Before They Develop Eczema, Study Finds

Researchers report in mSystems that infants experienced an enrichment in Clostridium sensu stricto 1 and Finegoldia and a depletion of Bacteroides before developing eczema.

Acute Myeloid Leukemia Treatment Specificity Enhanced With Stem Cell Editing

A study in Nature suggests epitope editing in donor stem cells prior to bone marrow transplants can stave off toxicity when targeting acute myeloid leukemia with immunotherapy.