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IP Roundup: IntegenX, NRCC, Callida Genomics, DNA Chip Research, Illumina, and More

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Title: Microfluidic devices with mechanically-sealed diaphragm valves.
Patent Number: 8,763,642
Filed: Feb. 23, 2012
Lead Inventor: Mattias Vangbo, IntegenX


Title: Ultrasensitive detection of target using target-ready particles.
Patent Number: 8,765,369
Filed: July 11, 2008
Lead Inventor: Sebastian Dubus, National Research Council of Canada


Title: Method for sequencing polynucleotides by forming separate fragment mixtures.
Patent Number: 8,765,375
Filed: Aug. 8, 2013
Lead Inventor: Radoje Drmanac, Callida Genomics


Title: Nucleic acid sequence analysis from combined mixtures of amplified fragments.
Patent Number: 8,765,379
Filed: Jan. 31, 2011
Lead Inventor: Radoje Drmanac, Callida Genomics


Title: Genome sequence analysis using tagged amplicons.
Patent Number: 8,765,382
Filed: Aug. 23, 2013
Lead Inventor: Radoje Drmanac, Callida Genomics


Title: Method of elongating DNA through immobilizing primer DNA chains on a substrate, a method of amplifying a DNA chain.
Patent Number: 8,765,417
Filed: Nov. 29, 2005
Lead Inventor: Kenji Kinoshita, DNA Chip Research


Title: Optically encoded particles.
Patent Number: 8,765,484
Filed: Jan. 31, 2003
Lead Inventor: Michael Sailor, University of California


Title: Methods and systems for controlling liquids in multiplex assays.
Patent Number: 8,765,486
Filed: Nov. 20, 2012
Lead Inventor: Chad DeRosier, Illumina


Title: Chip production, hybridization, and data interpretation for antibody and protein microarrays.
Patent Number: 8,765,641
Filed: March 18, 2005
Lead Inventor: Hyesook Kim, Detroit R&D

The Scan

Mosquitos Genetically Modified to Prevent Malaria Spread

A gene drive approach could be used to render mosquitos unable to spread malaria, researchers report in Science Advances.

Gut Microbiomes Allow Bears to Grow to Similar Sizes Despite Differing Diets

Researchers in Scientific Reports find that the makeup of brown bears' gut microbiomes allows them to reach similar sizes even when feasting on different foods.

Finding Safe Harbor in the Human Genome

In Genome Biology, researchers present a new approach to identify genomic safe harbors where transgenes can be expressed without affecting host cell function.

New Data Point to Nuanced Relationship Between Major Depression, Bipolar Disorder

Lund University researchers in JAMA Psychiatry uncover overlapping genetic liabilities for major depression and bipolar disorder.