Illumina of San Diego has received US Patent No. 8,333,325, "Optical reader system for substrates having an optically readable code." The described system includes a source light assembly that has a code-reading beam and a fluorescence-excitation beam that are configured to illuminate encoded substrates. According to the patent, the substrates have optically readable codes that provide output signals when the code-reading beam is projected on them. These output signals are indicative of the codes.