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Fluidigm of South San Francisco, Calif., has received US Patent No. 8,591,834, "High efficiency and high precision microfluidic devices and methods." The patent describes high-density microfluidic devices and methods that provide precise metering of fluid volumes and efficient mixing of the metered volumes. According to the patent, a first solution is introduced into a segment of a flow channel in fluidic communication with a reaction chamber.

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