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IP Roundup: Curiox Biosystems, Callida Genomics, Pharmaseq, Dako Denmark

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Title: Use of chemically patterned substrate for liquid handling, chemical and biological reactions.
Patent Number: 8,784,752
Filed: Oct. 21, 2010
Lead Inventor: Namyong Kim, Curiox Biosystems


Title: Random array DNA analysis by hybridization.
Patent Number: 8,785,127
Filed: Oct. 1, 2012
Lead Inventor: Radoje Drmanac, Callida Genomics


Title: Metal nanoparticle structures for enhancing fluorescence-based assays.
Patent Number: 8,785,352
Filed: Nov. 3, 2011
Lead Inventor: Wlodek Mandecki, Pharmaseq


Title: Information notification sample processing system and methods of biological slide processing.
Patent Number: 8,788,217
Filed: Jan. 23, 2013
Lead Inventor: Gordon Feingold, Dako Denmark

The Scan

Expanded Genetic Testing Uncovers Hereditary Cancer Risk in Significant Subset of Cancer Patients

In Genome Medicine, researchers found pathogenic or likely pathogenic hereditary cancer risk variants in close to 17 percent of the 17,523 patients profiled with expanded germline genetic testing.

Mitochondrial Replacement Therapy Embryos Appear Largely Normal in Single-Cell 'Omics Analyses

Embryos produced with spindle transfer-based mitochondrial replacement had delayed demethylation, but typical aneuploidy and transcriptome features in a PLOS Biology study.

Cancer Patients Report Quality of Life Benefits for Immune Checkpoint Inhibitors

Immune checkpoint inhibitor immunotherapy was linked in JAMA Network Open to enhanced quality of life compared to other treatment types in cancer patients.

Researchers Compare WGS, Exome Sequencing-Based Mendelian Disease Diagnosis

Investigators find a diagnostic edge for whole-genome sequencing, while highlighting the cost advantages and improving diagnostic rate of exome sequencing in EJHG.