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IP Roundup: Commissariat a l'Energie Atomique, Biomerieux, Singapore Agency for Science Technology and Research, Irori Technologies

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Commissariat a l'Energie Atomique of Paris and Biomérieux of Marcy l'Etoile, France, have received US Patent No. 8,216,827, "Device for bioassays with integrated detector." A device is described that includes a substrate, including a fluidic chamber formed as an aperture in the substrate, and channels formed in the substrate to circulate a fluid to be analyzed through the fluidic chamber; and a semiconductor device mounted in a cut-out at the bottom of the fluidic chamber, the cut-out extending through the substrate. According to the patent, the semiconductor device includes a front face disposed in the fluidic chamber, where the front face has an optical detector that is in contact with the fluid to be analyzed in the fluidic chamber, and a rear face disposed outside the fluidic chamber opposite the front face that includes electrical contact pads that can be used to electrically connect the optical detector to an external device.


The Agency for Science, Technology and Research of Singapore has received US Patent No. 216,855, "Method of processing a biological and/or chemical sample." A fluid droplet is described that includes an inner phase and an outer phase, where the outer phase is immiscible with the inner phase, the outer phase is surrounding the inner phase, and the inner phase includes the biological and/or chemical sample. The fluid droplet also contains magnetically attractable matter. A method of disposing the droplet on a surface and performing a process on a biological or chemical sample in the droplet is also claimed. According to the patent, the droplet can also be disposed on a DNA array for hybridization.


Irori Technologies of San Francisco has received US Patent No. 8,219,327, "Multiplexed assay using encoded solid support matrices." The patent describes a support matrix consisting of a substrate and a memory device with an optically encoded identifier to identify molecules attached to the substrate. According to the patent, the molecules are exposed to processing conditions and then are placed within the path of an optical detector adapted to read the optically encoded identifier and measure biochemical processes on each support matrix.

The Scan

For Better Odds

Bloomberg reports that a child has been born following polygenic risk score screening as an embryo.

Booster Decision Expected

The New York Times reports the US Food and Drug Administration is expected to authorize a booster dose of the Pfizer-BioNTech SARS-CoV-2 vaccine this week for individuals over 65 or at high risk.

Snipping HIV Out

The Philadelphia Inquirer reports Temple University researchers are to test a gene-editing approach for treating HIV.

PLOS Papers on Cancer Risk Scores, Typhoid Fever in Colombia, Streptococcus Protection

In PLOS this week: application of cancer polygenic risk scores across ancestries, genetic diversity of typhoid fever-causing Salmonella, and more.