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IP Roundup: CapitalBio, Omega Optics, Canon, Life Technologies, Affymetrix, and Others

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Title: Calibration slide for fluorescence detection instruments and process of preparation.
Patent Number: 8,636,954
Filed: Nov. 22, 2004
Lead Inventor: Yu Ge, CapitalBio


Title: Packaged chip for multiplexing photonic crystal waveguide and photonic crystal slot waveguide devices for chip-integrated label-free detection and absorption spectroscopy with high throughput, sensitivity, and specificity.
Patent Number: 8,636,955
Filed: Sept. 9, 2012
Lead Inventor: Swapnajit Chakravarty, Omega Optics


Title: Method of determining the haplotype of multiple allelic genes.
Patent Number: 8,637,248
Filed: Nov. 30, 2007
Lead Inventor: Shin-ichiro Takahama, Canon


Title: Systems and methods for point-of-care amplification and detection of polynucleotides.
Patent Number: 8,637,250
Filed: May 13, 2010
Lead Inventor: Robert Jenison, Great Basin Scientific


Title: Microarrays and uses therefor.
Patent Number: 8,637,264
Filed: June 30, 2011
Lead Inventor: James Hoeffler, Life Technologies


Title: Microfluidic solution for high-throughput, droplet-based single molecule analysis with low reagent consumption.
Patent Number: 8,637,301
Filed: March 2, 2010
Lead Inventor: Jeff Wang, The Johns Hopkins University


Title: Method for single nucleotide polymorphism and mutation detection using real time polymerase chain reaction microarray.
Patent Number: 8,637,302
Filed: Oct. 5, 2011
Lead Inventor: Zhenhong Sun, Honeywell International


Title: System for photolithographic synthesis of polymer arrays.
Patent Number: 8,637,434
Filed: Sept. 28, 2012
Lead Inventor: Martin Goldberg, Affymetrix


Title: Integrated semiconductor bioarray.
Patent Number: 8,637,436
Filed: Aug. 24, 2007
Lead Inventor: Arjang Hassibi, California Institute Technology

The Scan

Positive Framing of Genetic Studies Can Spark Mistrust Among Underrepresented Groups

Researchers in Human Genetics and Genomics Advances report that how researchers describe genomic studies may alienate potential participants.

Small Study of Gene Editing to Treat Sickle Cell Disease

In a Novartis-sponsored study in the New England Journal of Medicine, researchers found that a CRISPR-Cas9-based treatment targeting promoters of genes encoding fetal hemoglobin could reduce disease symptoms.

Gut Microbiome Changes Appear in Infants Before They Develop Eczema, Study Finds

Researchers report in mSystems that infants experienced an enrichment in Clostridium sensu stricto 1 and Finegoldia and a depletion of Bacteroides before developing eczema.

Acute Myeloid Leukemia Treatment Specificity Enhanced With Stem Cell Editing

A study in Nature suggests epitope editing in donor stem cells prior to bone marrow transplants can stave off toxicity when targeting acute myeloid leukemia with immunotherapy.