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IP Roundup: CalTech, Samsung, OSU, Agendia, Fluidigm, Nestec, Roche NimbleGen, Columbia


Title: Microfabricated elastomeric valve and pump systems.
Patent Number: 8,656,958
Filed: Oct. 31, 2007
Lead Inventor: Marc Unger, California Institute of Technology

Title: Method and apparatus for disrupting cells and purifying nucleic acid using a single chip.
Patent Number: 8,658,359
Filed: April 5, 2011
Lead Inventor: In-ho Lee, Samsung Electronics

Title: Methods for diagnosing colon cancer using MicroRNAs.
Patent Number: 8,658,362
Filed: Feb. 28, 2012
Lead Inventor: Carlo Croce, Ohio State University

Title: Microfabricated crossflow devices and methods.
Patent Number: 8,658,367
Filed: May 18, 2012
Lead Inventor: Stephen Quake, California Institute of Technology

Title: MicroRNA-based methods and compositions for the diagnosis, prognosis and treatment of breast cancer.
Patent Number: 8,658,370
Filed: Jan. 31, 2008
Lead Inventor: Carlo Croce, Ohio State University

Title: Means and method for determining tumor cell percentage in a sample.
Patent Number: 8,658,371
Filed: Sept. 1, 2009
Lead Inventor: Paul Roepman, Agendia

Title: Antibody-based arrays for detecting multiple signal transducers in rate circulating cells.
Patent Number: 8,658,388
Filed: March 11, 2008
Lead Inventor: Jeanne Harvey, Nestec

Title: Microfluidic particle-analysis systems.
Patent Number: 8,658,418
Filed: July 13, 2009
Lead Inventor: Antoine Daridon, Fluidigm

Title: Whole proteome tiling microarrays.
Patent Number: 8,658,572
Filed: March 13, 2012
Lead Inventor: Tom Albert, Roche NimbleGen

Title: Photo-generated carbohydrate arrays and the rapid identification of pathogen-specific antigens and antibodies.
Patent Number: 8,658,573
Filed: Sept. 11, 2007
Lead Inventor: Denong Wang, Columbia University

The Scan

Positive Framing of Genetic Studies Can Spark Mistrust Among Underrepresented Groups

Researchers in Human Genetics and Genomics Advances report that how researchers describe genomic studies may alienate potential participants.

Small Study of Gene Editing to Treat Sickle Cell Disease

In a Novartis-sponsored study in the New England Journal of Medicine, researchers found that a CRISPR-Cas9-based treatment targeting promoters of genes encoding fetal hemoglobin could reduce disease symptoms.

Gut Microbiome Changes Appear in Infants Before They Develop Eczema, Study Finds

Researchers report in mSystems that infants experienced an enrichment in Clostridium sensu stricto 1 and Finegoldia and a depletion of Bacteroides before developing eczema.

Acute Myeloid Leukemia Treatment Specificity Enhanced With Stem Cell Editing

A study in Nature suggests epitope editing in donor stem cells prior to bone marrow transplants can stave off toxicity when targeting acute myeloid leukemia with immunotherapy.