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IP Roundup: CalTech, Samsung, OSU, Agendia, Fluidigm, Nestec, Roche NimbleGen, Columbia


Title: Microfabricated elastomeric valve and pump systems.
Patent Number: 8,656,958
Filed: Oct. 31, 2007
Lead Inventor: Marc Unger, California Institute of Technology

Title: Method and apparatus for disrupting cells and purifying nucleic acid using a single chip.
Patent Number: 8,658,359
Filed: April 5, 2011
Lead Inventor: In-ho Lee, Samsung Electronics

Title: Methods for diagnosing colon cancer using MicroRNAs.
Patent Number: 8,658,362
Filed: Feb. 28, 2012
Lead Inventor: Carlo Croce, Ohio State University

Title: Microfabricated crossflow devices and methods.
Patent Number: 8,658,367
Filed: May 18, 2012
Lead Inventor: Stephen Quake, California Institute of Technology

Title: MicroRNA-based methods and compositions for the diagnosis, prognosis and treatment of breast cancer.
Patent Number: 8,658,370
Filed: Jan. 31, 2008
Lead Inventor: Carlo Croce, Ohio State University

Title: Means and method for determining tumor cell percentage in a sample.
Patent Number: 8,658,371
Filed: Sept. 1, 2009
Lead Inventor: Paul Roepman, Agendia

Title: Antibody-based arrays for detecting multiple signal transducers in rate circulating cells.
Patent Number: 8,658,388
Filed: March 11, 2008
Lead Inventor: Jeanne Harvey, Nestec

Title: Microfluidic particle-analysis systems.
Patent Number: 8,658,418
Filed: July 13, 2009
Lead Inventor: Antoine Daridon, Fluidigm

Title: Whole proteome tiling microarrays.
Patent Number: 8,658,572
Filed: March 13, 2012
Lead Inventor: Tom Albert, Roche NimbleGen

Title: Photo-generated carbohydrate arrays and the rapid identification of pathogen-specific antigens and antibodies.
Patent Number: 8,658,573
Filed: Sept. 11, 2007
Lead Inventor: Denong Wang, Columbia University

The Scan

Breast Cancer Risk Related to Pathogenic BRCA1 Mutation May Be Modified by Repeats

Several variable number tandem repeats appear to impact breast cancer risk and age at diagnosis in almost 350 individuals carrying a risky Ashkenazi Jewish BRCA1 founder mutation.

Study Explores Animated Digital Message Approach to Communicate Genetic Test Results to Family Members

In the Journal of Genetic Counseling, the approach showed promise in participants presented with a hypothetical scenario related to a familial hereditary breast and ovarian cancer syndrome diagnosis.

Computational Tool Predicts Mammalian Messenger RNA Degradation Rates

A tool called Saluki, trained with mouse and human messenger RNA data, appears to improve mRNA half-life predictions by taking RNA and genetic features into account, a Genome Biology paper reports.

UK Pilot Study Suggests Digital Pathway May Expand BRCA Testing in Breast Cancer

A randomized pilot study in the Journal of Medical Genetics points to similar outcomes for breast cancer patients receiving germline BRCA testing through fully digital or partially digital testing pathways.