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IP Roundup: CalTech, Maven Technologies, Cancer Genetics, Fujifilm, Enzo Life Sciences

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The California Institute of Technology of Pasadena has received US Patent No. 8,557,199, "Self-powered microfluidic devices, methods and systems." The claimed device consists of microfluidic channels and a pressure source for pumping reagents through the channels. This pressure source consists of a reservoir that contains a substance adapted to create a pressure-generating reaction product, a trigger, and a buffer chamber.


Maven Technologies of Los Angeles has received US Patent No. 8,557,609, "Imaging electrophoresis system."The patent claims a method for identifying analyte molecules in a sample. Using an evanescent field imaging ellipsometry apparatus, an evanescent field is created above the surface of a bioarray. An electrophoresis apparatus is then used to establish an electrophoresis functioning electrical field extending in a direction laterally disposed to the bioarray, and for placing a sample for moving analytes within the sample. Users can then detect the binding events of molecules that are moved by electrophoresis functioning across the bioarray.


Cancer Genetics of Rutherford, NJ, has received US Patent No. 8,557,747, "Tool for diagnosis and prognosis of mature B-cell neoplasms." The patent provides a microarray that can be used in the diagnosis or prognosis of certain types of cancers, particularly mature B-cell neoplasms. The microarray contains genomic regions corresponding to regions where alterations, such as copy number alterations, at such locations correlate to specific, identifiable cancers.


Fujifilm of Tokyo has received US Patent No. 8,557,748, "Method for immobilization, physiologically active substance-immobilized carrier, carrier for immobilization, carrier, and process for producing carrier." The method includes bringing the solid phase carrier into contact with an acid anhydride functional group-containing silane coupling agent represented by a claimed formula, and carrying out a process of binding of the physiologically active substance to the acid anhydride functional group while maintaining the solid phase carrier after the contact at a specific temperature. A carrier, including a porous material treated with an acid anhydride functional group-containing silane coupling agent, a blocking agent that is immobilized to the porous material; and a method for producing it are also provided.


Enzo Life Sciences of Farmingdale, NY, has received US Patent No. 8,557,522, "Processes for detecting or quantifying more than one nucleic acid in library." The patent provides compositions and processes for analyte detection, quantification and amplification. Nucleic acid arrays and libraries of analytes are usefully incorporated into such processes. Universal detection elements, signaling entities and the like are employed to detect and if necessary or desirable, to quantify analytes. Amplification of target analytes are also provided by the patent.

The Scan

Genes Linked to White-Tailed Jackrabbits' Winter Coat Color Change

Climate change, the researchers noted in Science, may lead to camouflage mismatch and increase predation of white-tailed jackrabbits.

Adenine Base Editor Targets SCID Mutation in New Study

Researchers from the University of California, Los Angeles, report in Cell that adenine base editing was able to produce functional T lymphocytes in a model of severe combined immune deficiency.

Researchers Find Gene Affecting Alkaline Sensitivity in Plants

Researchers from the Chinese Academy of Science have found a locus affecting alkaline-salinity sensitivity, which could aid in efforts to improve crop productivity, as they report in Science.

International Team Proposes Checklist for Returning Genomic Research Results

Researchers in the European Journal of Human Genetics present a checklist to guide the return of genomic research results to study participants.