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IP Roundup: California Institute of Technology, Affymetrix, Toyota, Mbio Diagnostics, Illumina, and Others

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Title: Microfabricated elastomeric valve and pump systems.
Patent Number: 8,695,640
Filed: Jan. 27, 2012
Lead Inventor: Marc Unger, California Institute of Technology


Title: Miniaturized microparticles.
Patent Number: 8,697,334
Filed: Dec. 23, 2011
Lead Inventor: Randall True, Affymetrix


Title: Method of producing solid-phase body having immobilized microobject and the use thereof.
Patent Number: 8,697,349
Filed: Oct. 23, 2008
Lead Inventor: Fumihiko Hoshino, Toyota


Title: Heavy metal biosensor.
Patent Number: 8,697,338
Filed: Nathan Hillson, US Department of Energy
Lead Inventor: Oct. 23, 2008


Title: Integrated sample preparation and analyte detection.
Patent Number: 8,697,453
Filed: Aug. 30, 2010
Lead Inventor: James Heil, Mbio Diagnostics


Title: Generation and application of standardized universal libraries.
Patent Number: 8,697,607
Filed: June 17, 2004
Lead Inventor: Tao Chen


Title: Lighting design of high quality biomedical devices.
Patent Number: 8,698,101
Filed: Oct. 23, 2012
Lead Inventor: Claudia Jaffe, Lumencor


Title: Compensator for multiple surface imaging.
Patent Number: 8,698,102
Filed: Oct. 17, 2013
Lead Inventor: Wenyi Feng, Illumina

The Scan

Long COVID-19 Susceptibility Clues Contained in Blood Plasma Proteome

A longitudinal study in eBioMedicine found weeks-long blood plasma proteome shifts after SARS-CoV-2 infection, along with proteomic signatures that appeared to coincide with long Covid risk.

Tibetan Study Finds Adaptive Variant Influencing Skin Pigmentation

With a combination of phenotyping and genetic data, researchers document at PNAS a Tibetan-enriched enhancer variant influencing melanin synthesis and ultraviolet light response.

Domestication Linked to Nervous System Genes in Inbred Mouse Strains

Researchers highlighted more than 300 positively selected genes in domesticated mice, including genes linked to nervous system function or behavior in Genome Biology.

ALS Genetic Testing May Be Informative Across Age Ranges, Study Finds

Researchers in the journal Brain identified clinically actionable variants in a significant subset of older ALS patients, prompting them to point to the potential benefits of broader test use.