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IP Roundup: California Institute of Technology, Affymetrix, Illumina, Immucor, Progenika Biopharma

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Title: Microfluidic free interface diffusion techniques.
Patent Number: 8,709,152
Filed: Aug. 19, 2011
Lead Inventor: Carl Hansen, California Institute of Technology


Title: Analysis of methylation using nucleic acid arrays.
Patent Number: 8,709,716
Filed: Jan. 27, 2011
Lead Inventor: Yanxiang Cao, Affymetrix


Title: Generation of uniform fragments of nucleic acids using patterned substrates.
Patent Number: 8,709,717
Filed: April 2, 2010
Lead Inventor: Kevin Gunderson, Illumina


Title: Method of making an array of nucleic acid colonies.
Patent Number: 8,709,729
Filed: May 29, 2013
Lead Inventor: Mostafa Ronaghi, Illumina


Title: Analysis, secure access to, and transmission of array images.
Patent Number: 8,712,123
Filed: April 12, 2011
Lead Inventor: Xiongwu Xia, Immucor


Title: Methods of prognosing a rheumatoid arthritis remission phenotype.
Patent Number: 8,712,696
Filed: Nov. 2, 2009
Lead Inventor: Arrate Eguiara, Progenika Biopharma

The Scan

Genome Sequences Reveal Range Mutations in Induced Pluripotent Stem Cells

Researchers in Nature Genetics detect somatic mutation variation across iPSCs generated from blood or skin fibroblast cell sources, along with selection for BCOR gene mutations.

Researchers Reprogram Plant Roots With Synthetic Genetic Circuit Strategy

Root gene expression was altered with the help of genetic circuits built around a series of synthetic transcriptional regulators in the Nicotiana benthamiana plant in a Science paper.

Infectious Disease Tracking Study Compares Genome Sequencing Approaches

Researchers in BMC Genomics see advantages for capture-based Illumina sequencing and amplicon-based sequencing on the Nanopore instrument, depending on the situation or samples available.

LINE-1 Linked to Premature Aging Conditions

Researchers report in Science Translational Medicine that the accumulation of LINE-1 RNA contributes to premature aging conditions and that symptoms can be improved by targeting them.