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IP Roundup: AIST, Cold Spring Harbor Laboratory, Intel, Agilent Technologies, and Others

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Title: Variable pitch array spotter.
Patent Number: 8,663,577
Filed: April 17, 2009
Lead Inventor: Hiroki Aoki, Japan's National Institute of Advanced Industrial Science and Technology


Title: Use of representations of DNA for genetic analysis.
Patent Number: 8,663,917
Filed: March 30, 2005
Lead Inventor: Michael Wigler, Cold Spring Harbor Laboratory


Title: Enzymatic signal generation and detection of binding complexes in stationary fluidic chip.
Patent Number: 8,664,008
Filed: July 6, 2012
Lead Inventor: David Liu, Intel


Title: Probes for specific analysis of nucleic acids.
Patent Number: 8,664,164
Filed: May 16, 2012
Lead Inventor: Olof Ericsson, Agilent Technologies


Title: Optical Biosensors
Patent Number: 8,664,363
Filed: Jan. 24, 2008
Lead Inventor: Carnegie Mellon University

The Scan

Lung Cancer Response to Checkpoint Inhibitors Reflected in Circulating Tumor DNA

In non-small cell lung cancer patients, researchers find in JCO Precision Oncology that survival benefits after immune checkpoint blockade coincide with a dip in ctDNA levels.

Study Reviews Family, Provider Responses to Rapid Whole-Genome Sequencing Follow-up

Investigators identified in the European Journal of Human Genetics variable follow-up practices after rapid whole-genome sequencing.

BMI-Related Variants Show Age-Related Stability in UK Biobank Participants

Researchers followed body mass index variant stability with genomic structural equation modeling and genome-wide association studies of 40- to 72-year olds in PLOS Genetics.

Genome Sequences Reveal Range Mutations in Induced Pluripotent Stem Cells

Researchers in Nature Genetics detect somatic mutation variation across iPSCs generated from blood or skin fibroblast cell sources, along with selection for BCOR gene mutations.