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The University of California of Oakland has received US Patent No. 7,897,684, "Conjugated polymers suitable for strand-specific polynucleotide detection in homogeneous and solid state assays." The patent describes a strand-specific polynucleotide sensing method performed on an array based on surface-bound peptide nucleic acids and water-soluble cationic conjugated polymers. The main transduction mechanism in the method operates by taking advantage of the net increase in negative charge at the PNA surface, which occurs upon strand-specific DNA hybridization.

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