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IP Roundup: Feb 8, 2011

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Seiko Epson of Tokyo has received US Patent No. 7,883,901, "Biogenic substance detector and biogenic substance detection method." The patent describes a biogenic substance detector containing multiple chambers for hybridizing a target and a probe; and a passage provided between the chambers. According to the patent, the cross-sectional area of the passage taken perpendicularly to the chamber-passage alignment direction is smaller than the cross-sectional area of each chamber taken perpendicularly to the chamber-passage alignment direction. A probe-fixing area is provided over the entire inside wall of each chamber. In the hybridization step, the sample solution is made to move back and forth within the chambers and the passage is used as a pump.


Boston Probes of Bedford, Mass., has received US Patent No. 7,884,053, "Methods, kits and compositions pertaining to combination oligomers and libraries for their preparation." The patent describes the block synthesis of combination oligomers in the absence of a template, as well as related methods, kits, and libraries.


Fujifilm of Tokyo has received US Patent No. 7,884,201, "Method for separating and purifying RNA." The patent describes a method for separating and purifying RNA. The method includes the steps of passing a sample solution containing a nucleic acid, a washing solution, and a recovering solution through a nucleic acid-adsorbing porous membrane to adsorb nucleic acid; and adsorbing, washing and recovering the solution. According to the patent, the sample solution is obtained by injecting a test sample containing blood, leukocytes, and an anticoagulant to a container; adding a hemolytic agent to the container to obtain a leukocyte pellet; adding a nucleic acid-solubilizing reagent to the leukocyte pellet to obtain a mixture solution; and adding a water-soluble organic solvent to the mixture solution to obtain the sample solution containing the nucleic acid.

The Scan

Germline-Targeting HIV Vaccine Shows Promise in Phase I Trial

A National Institutes of Health-led team reports in Science that a broadly neutralizing antibody HIV vaccine induced bnAb precursors in 97 percent of those given the vaccine.

Study Uncovers Genetic Mutation in Childhood Glaucoma

A study in the Journal of Clinical Investigation ties a heterozygous missense variant in thrombospondin 1 to childhood glaucoma.

Gene Co-Expression Database for Humans, Model Organisms Gets Update

GeneFriends has been updated to include gene and transcript co-expression networks based on RNA-seq data from 46,475 human and 34,322 mouse samples, a new paper in Nucleic Acids Research says.

New Study Investigates Genomics of Fanconi Anemia Repair Pathway in Cancer

A Rockefeller University team reports in Nature that FA repair deficiency leads to structural variants that can contribute to genomic instability.