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Affymetrix has received US Patent No. 7,745,178, "Complexity management of genomic DNA." The patent describes non-gel-based methods for amplifying a subset of the sequences in a sample in order to reduce nucleic acid sample complexity. This amplification can be accomplished by digesting a sample with two or more restriction enzymes and ligating adaptors to the fragments so that only a subset of the fragments can be amplified, according to the patent.

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Cancer researcher Alan Rabson has died at 92, the New York Times reports.

As the National Guideline Clearinghouse goes dark, the ECRI Institute says it will pick up the slack.

The Atlantic reports on private Facebook support groups for people who receive unexpected parentage results from direct-to-consumer genetic tests.

In Genome Research this week: sequencing method examines proteins parasite uses to evade immune system, L1 insertions in cancer, and more.