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IP Roundup: Jan 26, 2010

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Hewlett-Packard has received US Patent No. 7,651,665, "Microtray for handling biosubstances." The patent claims a microtray for handling biosubstances composed of a fluid-holding structure and a fluid-ejection structure. The fluid-holding structure includes an array of wells with each well configured to contain at least one biosubstance, according to the patent. The fluid-ejection structure is in communication with the fluid-holding structure and is configured to dispense the biosubstance onto a target media.


The University of Texas of Austin has received US Patent No. 7,651,850, "Image and part recognition technology." The patent claims a method for the recognition of images that includes the use of alignment markers. The image recognized may be a pattern from an array, a character, a number, a shape, or irregular shapes, according to the patent. More specifically, a method is provided for discriminating between images by accounting for the orientation of the image. The size or location of alignment markers may provide information about the orientation of an image, for instance. Information about the orientation of an image may reduce false recognitions, according to the authors. The described image recognition method may be used with identification markings, biosensors, microfluidic arrays, and optical character recognition systems.


The University of Texas has also received US Patent No. 7,651,868, "Method and system for the analysis of saliva using a sensor array." The patent claims a system for the rapid characterization of analytes in saliva. The described system includes a light source, a sensor array, and a detector. The sensor array is formed from a supporting surface that contains a number of cavities. According to the patent, chemically sensitive particles are positioned within the cavities that produce a signal when a receptor, coupled to the particle, interacts with the cardiovascular risk-factor analyte and the particle-analyte complex is visualized using a visualization reagent. Using pattern recognition techniques, the analytes within a multi-analyte fluid may then be characterized.


IBM has received US Patent No. 7,651,872, "Discrete nano-textured structures in biomolecular arrays, and method of use." The patent claims a biomolecular array including a substrate across which is distributed an array of discrete regions of a porous substance formed from a porogen-containing organosilicate material. The porous substance is designed to bind chemical targets useful in biotechnology applications, such as gene expression, protein, antibody, and antigen experiments, according to the patent. The regions are preferably optically isolated from each other and may be shaped to enhance detection of optical radiation emanating from the porous substance, such as a result of irradiation of the regions with ultraviolet light. The discrete regions may be configured as microscopic wells within the substrate, or they may reside on top of the substrate in the form of microscopic mesas, the patent states.


The Electronics and Telecommunications Research Institute of Daejeon-Shi, Korea, has received US Patent No. 7,652,370, "Plastic microfabricated structure for biochip, microfabricated thermal device, microfabricated reactor, microfabricated reactor array, and micro array using the same." According to the patent, the plastic microfabricated structure is fabricated to allow photolithography to be performed. The structure also includes a heater, a temperature sensor for sensing a temperature, an electrode, and an electrode pad so that uniform temperature control is possible. Various samples can therefore be thermally treated at a fast speed to obtain their reaction and analysis, the patent states.

The Scan

Genome Sequences Reveal Range Mutations in Induced Pluripotent Stem Cells

Researchers in Nature Genetics detect somatic mutation variation across iPSCs generated from blood or skin fibroblast cell sources, along with selection for BCOR gene mutations.

Researchers Reprogram Plant Roots With Synthetic Genetic Circuit Strategy

Root gene expression was altered with the help of genetic circuits built around a series of synthetic transcriptional regulators in the Nicotiana benthamiana plant in a Science paper.

Infectious Disease Tracking Study Compares Genome Sequencing Approaches

Researchers in BMC Genomics see advantages for capture-based Illumina sequencing and amplicon-based sequencing on the Nanopore instrument, depending on the situation or samples available.

LINE-1 Linked to Premature Aging Conditions

Researchers report in Science Translational Medicine that the accumulation of LINE-1 RNA contributes to premature aging conditions and that symptoms can be improved by targeting them.