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IP Roundup: Jul 28, 2009


Schott of Mainz, Germany, has received US Patent No. 7,566,672, "Glass composition exclusively consisting of oxides which already at low temperatures form volatile fluorides by reaction with fluorine and its use." The claimed glass is advantageous for microstructuring, especially reactive ion etching with fluorine and fluorine compounds, and has a glass composition based on oxide content, according to the patent. Microstructure components, such as microarrays, fresnel lenses, microwafers, or micro lens wafers, made by a method including reactive ion etching from the glass are also claimed.

Boston Probes of Bedford, Mass., has received US Patent No. 7,566,420, "Methods, kits and compositions pertaining to combination oligomers and libraries for their preparation." The patent claims a kit that includes independently detectable combination oligomers, oligonucleotides, buffers, nucleotide triphosphates, a nucleic acid amplification master mix, and polymerase enzymes.

Intelligent Medical Devices of Cambridge, Mass., has received US Patent No. 7,566,533, "Clinically intelligent diagnostic devices and methods." The patent describes the "clinically intelligent design" of diagnostic devices such as microarrays and methods ways of making and using the devices in differential diagnoses of specific clinical symptoms or sets of symptoms. The described devices include various probes used to perform parallel screening of a number of analytes. According to the patent, the probes are clustered on the devices based on known clinical presentations of symptoms associated with specific diseases and disorders.

The Scan

Suicidal Ideation-Linked Loci Identified Using Million Veteran Program Data

Researchers in PLOS Genetics identify risk variants within and across ancestry groups with a genome-wide association study involving veterans with or without a history of suicidal ideation.

Algorithm Teases Out Genetic Ancestry in Individuals at Biobank Scale

Researchers develop an algorithm known as Rye to tease apart ancestry fractions in admixed individuals at a biobank-scale, applying it to 488,221 UK Biobank participants in Nucleic Acids Research.

Multi-Ancestry Analysis Highlights Comparable Common Variants at Complex Trait-Linked Loci

Researchers in Nature Genetics examine common variants implicated in more than three dozen conditions, estimating genetic effect similarities across ancestry tracts in admixed individuals.

Sick Newborns Selected for WGS With Automated Pipeline

Researchers successfully prioritized infants with potential Mendelian conditions for whole-genome sequencing or rapid whole-genome sequencing, as they report in Genome Medicine.