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The University of Missouri at Columbia has received US Patent No. 7,563,567, "Use of ECIST microarrays in an integrated method for assessing DNA methylation, gene expression and histone acetylation." The patent provides methods for the high-throughput, dual analysis of DNA methylation and gene expression, and triple analysis of DNA methylation, gene expression, and gene-associated histone acetylation in cancer cells using arrayed expressed CpG island sequence tags, or ECISTs.

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