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IP Roundup: Feb 3, 2009

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Optomec Design of Albuquerque, NM, has received US Patent No. 7,485,345 “Apparatuses and methods for maskless mesoscale material deposition.” The patent claims apparatuses and processes for the maskless deposition of electronic and biological materials. The described process is capable of the direct deposition of features with linewidths varying from the micron range up to a fraction of a millimeter, and may be used to deposit features on substrates with damage thresholds near 100 degrees Celsius. Deposition and subsequent processing may be carried out under ambient conditions, eliminating the need for a vacuum atmosphere, the patent states. The process may also be performed in an inert gas environment.


The University of Illinois of Urbana has received US Patent No. 7,485,419, “Biosensors based on directed assembly of particles.” The patent claims a sensor system for detecting an effector or cofactor. The system includes: a) a nucleic acid enzyme; b) a substrate for the nucleic acid enzyme, including a first polynucleotide; c) a first set of particles including a second polynucleotide that is at least partially complementary to the substrate, where the polynucleotide is attached to the particles at its 3' terminus; and d) a second set of particles including a third polynucleotide at least partially complementary to the substrate, where the polynucleotide is attached to the particles at its 5' terminus.


Cornell Research Foundation of Ithaca, NY, has received US Patent No. 7,485,424, “Labeled nucleotide phosphate (NP) probes.” The patent describes a method of sequencing a target nucleic acid molecule having a plurality of bases. In its principle, the temporal order of base additions during the polymerization reaction is measured on a molecule of nucleic acid. For example, the activity of a nucleic acid polymerizing enzyme on the template nucleic acid molecule to be sequenced is followed in real time. The sequence is deduced by identifying which base is being incorporated into the growing complementary strand of the target nucleic acid by the catalytic activity of the nucleic acid polymerizing enzyme at each step in the sequence of base additions, according to the patent.


Nanosphere of Northbrook, Ill., has received US Patent No. 7,485,470, “Method for attachment of silylated molecules to glass surfaces.” The patent claims a method for the efficient immobilization of silylated molecules such as silylated oligonucleotides or proteins onto unmodified surfaces such as a glass surfaces. The patent also claims compounds, devices, and kits for modifying surfaces such as glass surfaces.

The Scan

For Better Odds

Bloomberg reports that a child has been born following polygenic risk score screening as an embryo.

Booster Decision Expected

The New York Times reports the US Food and Drug Administration is expected to authorize a booster dose of the Pfizer-BioNTech SARS-CoV-2 vaccine this week for individuals over 65 or at high risk.

Snipping HIV Out

The Philadelphia Inquirer reports Temple University researchers are to test a gene-editing approach for treating HIV.

PLOS Papers on Cancer Risk Scores, Typhoid Fever in Colombia, Streptococcus Protection

In PLOS this week: application of cancer polygenic risk scores across ancestries, genetic diversity of typhoid fever-causing Salmonella, and more.